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DAS28 Calculator

Calculate your patient’s disease activity using the interactive DAS28 calculator below.

The disease activity score in 28 joints (DAS28) is a composite, numerical score combining several discrete measures of RA activity into a single grading of disease severity. This measure is used in both trials and clinical practice and was developed because one single measure cannot adequately represent disease activity in RA.1,2

EULAR recommendations on the management of early arthritis state that, in addition to structural damage and functional status, monitoring of disease activity should include the key components of the DAS28: tender and swollen joint count (TJC and SJC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level and patient’s global assessment of general health measured on a visual analogue scale (VAS). Arthritis activity should be assessed at 1–3 month intervals until remission is achieved.3

References

  1. van der Heijde D, et al. Judging disease activity in clinical practice in rheumatoid arthritis. First step in the development of a “disease activity score”. Ann Rheum Dis 1990; 49:916–920.
  2. Prevoo M, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38:44–48.
  3. Combe B, et al. EULAR recommendations for the management of early arthritis: Report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2007; 66:34–45.